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Stomach — MRCS Revision

🟡 The Stomach

Complete MRCS revision — anatomy, blood supply, peritoneal attachments, gastric physiology, H. pylori, peptic ulcer disease, gastric outlet obstruction, stress ulcers, gastric carcinoma, bariatric surgery, post-gastrectomy syndromes, and gastric volvulus.

Gastric Anatomy

Regions of the Stomach

The stomach is divided into five regions from proximal to distal: cardia (GOJ entry zone), fundus (dome above GOJ, contains gas on erect CXR), body (largest part, main secretory zone), antrum (hormonal regulation, pyloric glands), and pylorus (muscular sphincter controlling gastric emptying). The lesser curvature forms the medial border; the greater curvature forms the lateral border.

Stomach parts labelled
Stomach Regions — LabelledCardia, fundus, body, antrum and pylorus with their anatomical relationships and boundaries.
Stomach sphincters and pylorus labelled
Stomach Sphincters & PylorusLower oesophageal sphincter at the GOJ, pyloric sphincter, and structural relationships to adjacent structures.
Blood Supply

Lesser Curvature

Left + Right gastric arteries

  • Left gastric artery — direct branch of the coeliac trunk; largest contributor to lesser curvature; must be ligated during gastrectomy
  • Right gastric artery — from the hepatic artery (proper or common)
  • These two vessels anastomose along the lesser curvature

Greater Curvature

Left + Right gastroepiploic arteries

  • Left gastroepiploic artery — from the splenic artery
  • Right gastroepiploic artery — from the gastroduodenal artery (GDA)
  • These anastomose along the greater curvature
  • The GDA is a branch of the common hepatic artery

Short Gastric Arteries

Gastric fundus

  • 4–5 branches from the splenic artery
  • Supply the gastric fundus via the gastrosplenic ligament
  • Divided during total gastrectomy and splenectomy
  • Important: their division = the primary step in mobilising the greater curvature

Venous Drainage

All → portal system

  • Left gastric (coronary) vein → portal vein directly
  • Right gastric vein → portal vein
  • Right gastroepiploic vein → SMV
  • Left gastroepiploic + short gastric veins → splenic vein
  • Portal hypertension → gastro-oesophageal varices via left gastric vein

Lymphatic Drainage

Follows arterial supply

  • Left gastric territory → left gastric nodes → coeliac nodes
  • Right gastric territory → hepatic nodes
  • Fundus / short gastric territory → splenic nodes
  • Lesser curve overall → left gastric → coeliac
  • D2 dissection targets all named nodal stations

Nerve Supply

Vagus + sympathetic

  • Parasympathetic — vagus nerve (CN X): secretomotor and motor; left vagus → anterior surface; right vagus → posterior surface
  • Sympathetic — coeliac plexus (T6–T9): vasomotor, pain fibres; inhibits motility and secretion
  • Intrinsic — Auerbach’s plexus (myenteric) and Meissner’s plexus (submucosal)
Coeliac trunk and stomach blood supply diagram
Coeliac Trunk & Gastric Blood SupplyBranches of the coeliac trunk supplying the stomach — left gastric artery, splenic artery (short gastric + left gastroepiploic), and hepatic artery (right gastric + gastroduodenal → right gastroepiploic).
Transpyloric plane diagram
Transpyloric Plane (of Addison) — L1Key landmarks at L1: pylorus, fundus of gallbladder, neck of pancreas, superior mesenteric artery origin, hilum of both kidneys, and tip of 9th costal cartilages. Lies halfway between the jugular notch and the pubic symphysis.
Relations of the Stomach

Posterior Relations (Stomach Bed)

Lesser sac lies between stomach and these structures

Mnemonic: PAN SAD — Pancreas · Aorta/splenic artery · (left) Nephric structures · Spleen · Adrenal · Diaphragm (left crus)

  • Pancreas — body and tail; posterior gastric ulcer can erode the splenic artery running along the superior pancreatic border
  • Splenic artery — tortuous along superior pancreatic border
  • Left kidney and adrenal gland
  • Transverse mesocolon
  • Spleen

Anterior Relations

Covered by peritoneum anteriorly

  • Left lobe of liver — overlies the body and lesser curvature
  • Anterior abdominal wall — fundus and body directly related when liver is retracted
  • Diaphragm — fundus is closely related to the left hemidiaphragm

When an anterior duodenal or gastric ulcer perforates, contents spill into the peritoneal cavity → peritonitis. Free gas collects under the diaphragm on erect CXR.

Peritoneal Attachments

Lesser Omentum

Hepatogastric + Hepatoduodenal ligaments

Hepatogastric lig.From liver (porta hepatis) to the lesser curvature of the stomach. The “curtain” of the lesser omentum.
Hepatoduodenal lig.From liver to the first part of the duodenum. Contains the portal triad: portal vein (posterior), hepatic artery (left), common bile duct (right) — Pringle manoeuvre compresses this.
Free edgeThe right free edge of the lesser omentum forms the anterior boundary of the Epiploic Foramen (Foramen of Winslow).

Greater Omentum

Gastrocolic, Gastrosplenic, Gastrophrenic

Gastrocolic lig.Stomach to transverse colon. Part of the greater omentum. Must be divided to access the lesser sac (e.g. for pancreatitis drainage or oesophagectomy).
Gastrosplenic lig.Stomach (greater curve) to spleen. Contains short gastric arteries and left gastroepiploic artery. Divided during splenectomy.
Gastrophrenic lig.Stomach (fundus) to diaphragm. No major vessels. Divided during total gastrectomy.
Gastric Histology

The gastric wall has four layers: mucosa (surface epithelium + gastric glands + lamina propria + muscularis mucosae), submucosa, muscularis externa (oblique inner, circular middle, longitudinal outer — three layers unique to the stomach), and serosa. The mucosa varies by region: body/fundus has deep principal glands packed with parietal and chief cells; the antrum has shallower pyloric glands with G and D cells.

Gastric histology overview
Gastric Histology — OverviewLow-power view showing gastric mucosa with gastric pits (foveolae) and underlying glands. Note the distinct mucosal architecture compared to small bowel (no villi).
Gastric histology magnified
Gastric Histology — High PowerHigh-power view showing individual cell types within the gastric glands. Parietal cells are large with eosinophilic (pink) granular cytoplasm; chief cells are smaller with basophilic (blue/purple) cytoplasm from pepsinogen granules.
The Lesser Sac & Epiploic Foramen

The Lesser Sac (Omental Bursa) — Anatomy and Clinical Relevance

The lesser sac is a potential space posterior to the stomach, bounded anteriorly by the stomach and lesser omentum, posteriorly by the pancreas and stomach bed structures. It communicates with the greater sac via the Epiploic Foramen of Winslow.

Boundaries of the Epiploic Foramen (Winslow):
Anterior — hepatoduodenal ligament (contains portal triad)
Posterior — IVC (inferior vena cava)
Superior — caudate lobe of liver
Inferior — first part of duodenum

Clinical relevance of the lesser sac:
🔵 Pancreatic pseudocyst — fluid from acute pancreatitis tracks into the lesser sac (it is bounded and cannot easily escape), creating a pseudocyst. Drained into the posterior wall of the stomach (cystgastrostomy) or Roux-en-Y cystjejunostomy.
🔵 Surgical access — the lesser sac is entered via the gastrocolic ligament or lesser omentum to reach the pancreas, the posterior stomach, and the coeliac axis.
🔵 Epiploic foramen herniation — rare but life-threatening internal hernia through the foramen of Winslow.

Gastric Volvulus

Gastric volvulus is an abnormal rotation of the stomach around one of its two axes. It may be primary (no anatomical cause — laxity of gastric ligaments) or secondary (paraoeosphageal hernia, diaphragmatic defect, raised left hemidiaphragm). It can be acute (surgical emergency) or chronic (intermittent).

Borchardt’s Triad — Classic Presentation of Acute Gastric Volvulus

1️⃣ Sudden severe epigastric pain — often catastrophic in onset
2️⃣ Violent retching without vomiting — obstruction prevents vomiting
3️⃣ Inability to pass a nasogastric tube — twisted anatomy prevents NG passage

Acute gastric volvulus is a surgical emergency. Ischaemia and strangulation develop rapidly. Management: urgent endoscopic decompression (first-line if viable) or emergency laparotomy with derotation and gastropexy (definitive). Concurrent repair of any diaphragmatic defect or paraosophageal hernia is performed to prevent recurrence.

Organoaxial Volvulus

Most common — rotation around long axis

AxisRotation around the long axis of the stomach (line connecting the cardia to the pylorus)
DirectionGreater curvature rotates anteriorly and superiorly (most common) or posteriorly
RiskHigher risk of strangulation and ischaemia — the vessels are twisted along with the stomach
AssociationParaosophageal hernia, diaphragmatic defects, lax gastric ligaments

Mesenteroaxial Volvulus

Less common — rotation around short axis

AxisRotation around the short axis (line connecting the midpoints of the lesser and greater curvatures)
DirectionAntrum rotates anteriorly and superiorly relative to the cardia
RiskLower strangulation risk — less vascular compromise. More commonly presents as chronic/intermittent.
AssociationAbnormally mobile stomach, lax gastrocolic ligament
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